Klotho Ameliorates Chemically Induced Endoplasmic Reticulum (ER) Stress Signaling
نویسندگان
چکیده
منابع مشابه
Klotho ameliorates chemically induced endoplasmic reticulum (ER) stress signaling.
BACKGROUND Both endoplasmic reticulum (ER) stress, a fundamental cell response associated with stress-initiated unfolded protein response (UPR), and loss of Klotho, an anti-aging hormone linked to NF-κB-induced inflammation, occur in chronic metabolic diseases such as obesity and type 2 diabetes. We investigated if the loss of Klotho is causally linked to increased ER stress. METHODS We treat...
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ژورنال
عنوان ژورنال: Cellular Physiology and Biochemistry
سال: 2013
ISSN: 1421-9778,1015-8987
DOI: 10.1159/000350085